Hey Larry, the main point was missed. I stated ROT in my slight drift there. The main point was
If the OEM bothers to show fastener installation in a certain orientation, follow it. If unsure or questionable, get clarification.
There could be reasons that aren't obvious e.g. later assembly/fab could limit tool access, etc. If it's something with a low profile like a clevis bolt, more scrutiny should be given. It was specified for a reason.
There are many associated instances/accidents where related mistakes have had serious consequences, unfortunately. One of the earliest that I remember was an early USAF jet (F86 Sabre??). The tech placed some bracket bolts in per convention (threads down) ignoring the engineering releases that specified otherwise. He assumed those were incorrect. Under the high drag load of jet speeds, the wings flexed enough where the ailerons would bind on the improperly installed fastener. The resulting constant roll made survivable ejections impossible. Extreme example I know, but follow the OEM releases.