At my day job working heavy jet overhaul, we use Proseal and derivatives for pretty much everything that needs sealed, for pressurization, fuel tanks, and water incursion. In the large aircraft world, every piece of skin is installed "wet' with fay surface sealant, and the finished edges are wiped smooth and clean. Afterwards, some are edge sealed as you are describing. In GA/Experimental, that edge is extremely thin, thus the fillet edge seal is very minimal. Sealant is usually applied to PROPERLY primed skin surfaces. Final external paint preparation requires a gentle hand and Scotchbrite scuff prior to paint. I also work as an APIA in the GA world, and built my -4. I fay/seam sealed only 1 seam on my plane, and that was the belly seam down the centerline. I am not a fan of trying to seam seal light aircraft, as there is minimal sealant retention area, and a good paint job over good sheetmetal work will leave a filled joint. Bigger gaps as noahhl mentioned are best filled with Proseal type material as it is compatible with topcoats and resistant to oils and such. if you lived close by, Id give you all the tubes of Proseal you want.