I remember as a hot rod'er teenager a few years ago

rolleyes: many decades) I made high tension ignition leads, like MSD. I always found those crimps challenging. I don't think there is anything wrong per se proactively replacing spark plug wires. For me visual inspection and engine running normal is goodness.
As far a ohm reading read up on that. A typical multi-meter draws a very small current, typically in the range of microamps (µA) and voltage is usually very low, often in the millivolt range, for resistance reading. In operation you are pulsing 20kV or double that. I'm not up on how to TEST these wires. In car world it was just replace them proactively unless they had physical damage or failed completely. I have a diesel car and an EV now. My motorcycle has spark plug coil packs on the plug. So no plug wires to deal with on my earth bound vehicles.
However, the spark plug wires can wear out and breakdown over time, which can lead to misfires and loss of power. Looking at the car world, consciences is around 60,000 miles, say 6 years. Then I read from the WWW even "lifetime" plug wires will begin to have the insulation fail after 30-40,000 miles, or 2-4 years? Of course most modern car engines have no plug wires, they have individual coil packs on each plug, and sometimes very short high tension leads. On the other hands people that do use sparkplug wires drive with same plug wires for the life of the car.
I'd say aircraft have more heat and vibration than a car, but aircraft accrue also less hours. So how many hours in 10 years?