I did this on my carb a few years back. There was a post some 15 years ago on how to do this. Basically you put a board on the drill press and drill down through it with a diameter just big enough to fit the nozzle (so it holds the nozzle and aligns it with the bit). Then just drill slowly, with the next size bit and use lots of oil.
The Story: I did an exchange instead of rebuilding the one I had. The new one was at peak EGT with the mixture at full rich. Sent it back and it flow tested within spec, but still had the same problem. So I called again and told them I wanted it drilled out. I first got a "No No, don't don't drill it out... let me let you talk to the tech". Then I spoke to the tech who said "don't do it... there are steps and stuff an you will ruin the nozzle". Then I told him I was experimental and he said, "Oh, no problem and I'll drill it out for you for $100". A new nozzle was less than $100, so I did it myself with the above procedure and it worked fine. I have some photos of the process I can find if you need, but it was dirt simple.