Asymmetric G Limits
Asymmetric G limits are often specified for fighters. Newer airplanes with either an "OWS" (overload warning system) or true fly-by-wire either warn you or preclude an over-G condition from occuring. Older airplanes (including the T-38) were/are dependent on the pilot observing limits (which is why they tend to end up bent!).
Depending on how the plane is designed, asymmetric conditions (application of simultaneous flight controls about two axis) may be accounted for in the specified G limits--i.e., it can be designed in. If not specified, a rule of thumb is to reduce specified limits by 20%--Doug's 1/3 ROT is just about perfect from a handling perspective. For typical recreational aerobatics, 4 G's is generally plenty. In a typical aerobatic RV loaded within designer's limits, asymetric application of controls isn't of much concern if you operate within this envelope.
The real discussion is loaded vs. unloaded rolling. This is sometimes refered to as "lift vector control." The lift vector extends straight up from your seated position in the cockpit and it's essentially "where the lift is pointed." The short answer here is if your intent is to apply maximum allowable G (assuming you're flying faster than corner velocity [maneuvering speed] and have 6 G's available), it's generally best to have the lift vector set where you want it prior to application of maximum allowable G. Energy bleed rates are high at 6 G's (if you have airspeed under control!), so you're not going to stay there very long.
Thread drift. One thing to keep in mind with any RV is the amount of aerodynamic G available at speeds above corner velocity. Due to the wide speed band (margin between stall and Vmax), the amount of instantaneous G you can develop with a stick snatch is impressive and more than enough to reak havoc, even if the wings or tail don't come off. Our RV-4 at 1375 lbs gross is capable of generating 9 G's (ultimate design load limit) at 165 MPH CAS. At 200 MPH (cruise descent in smooth air at an appropriate altitude), 13.2 G's are possible. During maneuvering flight (i.e., aerobatics, unusual attitudes, etc.), this phenominon can manifest itself if the velocity vector (where the airplane is going) is buried and the airplane is allowed to acellerate above corner. Any time you are above corner/maneuvering speed, an over-G is possible with improper application of the flight controls.
Cheers,
Vac