I have done Appleton a couple of times. Very easy in and park. There are shuttle buses directly to OSH. I stayed at a B&B in Appleton so rented a car in the terminal which is about 100 ft walk from the FBO where the van drops/picks you up. All is very easy, and well organized.
Everything is great except that your plane is located out in the field in the middle of the airport. It requires a van to take you out to your plane. I find it very inconvienent in the middle of OSH week when I want to check on my plane or drop something off. Especially like to check my plane if a storm rolled though and I just want to make sure it is still tied down. It is a couple hour ordeal to wait for a shuttle, go to your plane, do what you need to do, wait for a return shuttle, get back to the FBO.
This is even worse when wanting to leave in a hurry. Both times there I was leaving with storms in the area. You can't go out to your plane to wait for a break since there is no shelter out in the field. You need to wait in the FBO and it makes timing a departure difficult due to process of getting out to your plane. I was lucky both times to see a break in the radar, get in van, get to plane, load plane, preflight, airport opened to VFR, take-off and out before next wave of Wisconsin storms came by. I could easily been caught for hours sitting in the FBO.
In short, loved Appleton just do not like the access to plane. It is not easy like you get staying on the field at OSH.