A challenge but sounds rewarding
To add to Ross you will need some custom exhaust and special exhaust parts, turbo flanges and couplers. Check out Burns exhaust:
http://www.burnsstainless.com/
And
http://www.aircraftexhaust.net/ may be able to weld up the whole thing. If you can properly fab and weld stainless all the better. The exhaust in a turbo system is the key to system reliability.
You are going with a one off custom set-up. There are no kits for your application. You could look at a Turbo 540 set-up in a Ted Smith/Piper Aerostar, Navajo and Malibu. Not sure that will help too much. You have limited room. As Ross mentioned many turbos go high and behind the engine. To do that the engine mount needs to cantilever the engine further from the firewall to make room for the turbo.
No inter-cooler simple diagram.
In my opinion engine life may go down, it seems to me. Simply because you will run it harder and hotter. As you climb there is less air to cool the engine which is making as much power as it would @ 8,000 feet not turboed, as you will now be making at FL180. So plan on a bigger oil cooler as well. As Ross suggest inter-coolers are a must, but there are non-intercooled aircraft installations. I know that would be very hard on the engine.
To put the bug in your ear, while you are at it, what about making it a product, a business? Make several "kits" or design it to be reproduced and "kit-ed". You could sell your turbo set-up to other RV-10 builders. It won't be cheap, but you could may be make some money on it?
You will spend time designing, engineering, fabricating but it can be done. The more you can do, weld stainless and machine parts, the better it will be. Depending on where you live you may have many options for sub-vendors to do the fab work, but that will add cost. It sounds exciting and a great learning experience. All the best, whether you go for it.
This is my objection to turbos in RV's: time, work, weight and cost. However turbos do have their advantage. I'm not so worried about exceeding your Vne, Vno or flutter margin
as long as you operate with that in mind. A lot of planes (jets) I fly can exceed Vne/Vmo at will in level flight at any altitude.
It will be a challenge, like stuffing 10 lbs of stuff in a 5 lbs sack (click thumbnail).
A custom turbo conversion for cars cost about $3500-$5700. So you can plan on putting that much into parts at least. One turbo can cost $900 to $1500. Also you will have to vent and plumb the larger oil cooler and inter-cooler'(s) so not to cause more cooling drag. Sounds like fun.
In your research check out Rajay. They have 27 STC's going back to 1962 for converting ATMO GA planes with turbochargers. Here is one of their STC on a IO-540 with twin turbos:
http://www.airweb.faa.gov/Regulator...2571AA00593317?OpenDocument&Highlight=se 6 we
Here is a site that supports Rajay parts and list all Rajay STC's. Not saying you should copy their systems, but they may have some ideas or even parts you can adapt.
http://www.rajayparts.com/13701.html