Priming sealant
In the jet world tank sealant is used for more than fuel tanks. It is used it on the edges of fairings, to fair a out the edges of windshields, to seal the gaps of access covers and nav lenses and to seal the cabin pressure vessel. It all gets primed and painted with rest of the plane. My experience is primer and paint will stick to sealant pretty well but not as good as metal. If the sealant gets primed painted before the sealant is completely dry the primer and paint will eventually will come off. I sprayed primer on the outside of my RV6 fuel tanks and the primer has adhered fine to the sealant.