One thing to keep in mind is the difference between predrilled and prepunched. As Bob said, drill them to full size. This does a couple of things, obviously makes them very slightly larger, aligns them perfectly (although they usually are anyway,) AND removes the tool marks that are perpendicular to the surface. These are the marks that can cause cracking when the material is dimpled. As the material is dimpled, it is stretched. #40 dimples aren't likely to crack, but #30 and especially larger dimples for screws are more likely to.
There has been some debate as to whether it is necessary to drill out 3/32" holes to #40 before dimpling. It is your airplane, but I think Bob said it right--cleco, drill, deburr, dimple, and rivet, in that order. Cutting corners can save time, but can lead to problems later. The old "Pay me now, or pay me later." can apply here, in matters of time as well as expense.
Bob