Having just done a glass panel upgrade in my RV4 to IFR capablility, here's my thoughts. While I put in a GRT 8.4" Sport, the new AFS units also do pretty much the same job. You can get them with built in GPS's although they are not TSO'd so you cannot use them to file /G or shoot any type of GPS approach. I did not go with a certified GPS and opted to limit myself to doing VOR, LOC, ILS navigation and approaches with an SL30. These two EFIS's can integrate with an ARINC module to give you GPSS & GPSV from a Trutrak or Trio autopilot. The CDI is displayed on the EFIS so no need for a separate unit and the SL30 is a fantastic Nav/Comm that allows you to display the standby radial for intersections and fixes.
Both the GRT and AFS units will give you the ability to do a triple split screen so you can display your flight instruments, map, and engine data all at one time.
If you really want IFR GPS capability you could probably fit an older GX55 or GX60 in the panel. The RV4 panel is very small so it makes putting into the panel a GNS430W difficult and if you go with the smaller sized EFIS, it will be difficult to read all the data it is displaying with the triple split screen.