Easy, less expensive alternative to the above (for those of us on a budget

):
For size 6 screws: silver cleco the nutplate through the threads (of the nutplate) onto the #40 pilot hole in whatever structure you're attaching the nutplate to. Drill one ear #40, insert another cleco. Drill opposite ear to #40. Drill pilot hole up to size 6 (#28). Done.
For size 8 screws: copper cleco the nutplate through the threads (of the nutplate) onto the #30 pilot hole in whatever structure you're attaching the nutplate to. Drill one ear #40, insert another cleco. Drill opposite ear to #40. Drill pilot hole up to size 8 (#19). Done.
Used this method all throughout the airframe, including screwed down baggage floors. No big deal.