You want to use a good quality thread sealant. I used Leak Lock by Highside Chemicals on everything. Available at many HVAC or Refrigeration supply houses. I tighten by feel. Your seal is made at the thread root with the sealant, so overtightening will not fix a leak. If I did not have at least 4 threads engaged on 1/8" or 1/4" NPT fittings, I would remove, clean, use thread cutting oil and re-tap the fitting. Upon tightening properly, I would say 4-6 threads engaged.
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Good judgment comes from experience, and a lot of that comes from bad judgment.
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