I live in Hillsboro (well, Aloha, but i'm about 10 min from Hillsboro airport) and commute to Salem. Sometimes I get to take the airplane, like today.
It takes about an hour to make the drive.
To commute by plane...
1. 12 minutes out to the airport.
2. 3 minutes of preflight.
3. 5 minutes to get the engine warm and taxi to the end of the runway.
4. 15 minutes enroute.
5. Another 5 minutes securing the plane.
6. 5 more minutes getting into my buddies hangar, changing into bike shoes, and putting air in the bicycle tire.
7. 15 minutes to bike to the office (with traffic).
For a net total travel time of... One hour and two minutes. That's a very optimistic estimate, normally it takes an hour and 15 minutes. Today took longer because I had a cup of coffee with my hangar neighbor before leaving this morning. Also, the return took longer because I had to divert due to weather (i'm VFR only).
Many times i'll practice maneuvers or make an extra landing along the way. So, while it takes me longer to commute this way, it is very enjoyable.