My partner and I, in our sixties, have always run 1 tank out of gas, engine dies, switch tanks, start up again in a 1959 Comanche 250 with a Lyc O-540. Partner doing it for 34 years and his father before that. No adverse affects. I think it's good real world training as long as you have outs; altitude and somewhere to set it down.
And you always know that the tank you're on is the only one with remaining fuel if things ever get tight
